Volume 2 Issue 4
December  2023
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Yue Niu, Ze Qin, Ying Zhang, Chao Chen, Sha Liu, Hu Chen. Expanding the potential of biosensors: a review on organic field effect transistor (OFET) and organic electrochemical transistor (OECT) biosensors[J]. Materials Futures, 2023, 2(4): 042401. doi: 10.1088/2752-5724/ace3dd
Citation: Yue Niu, Ze Qin, Ying Zhang, Chao Chen, Sha Liu, Hu Chen. Expanding the potential of biosensors: a review on organic field effect transistor (OFET) and organic electrochemical transistor (OECT) biosensors[J]. Materials Futures, 2023, 2(4): 042401. doi: 10.1088/2752-5724/ace3dd
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Topical Review •
OPEN ACCESS

Expanding the potential of biosensors: a review on organic field effect transistor (OFET) and organic electrochemical transistor (OECT) biosensors

© 2023 The Author(s). Published by IOP Publishing Ltd on behalf of the Songshan Lake Materials Laboratory
Materials Futures, Volume 2, Number 4
  • Received Date: 2023-06-20
  • Accepted Date: 2023-07-03
  • Publish Date: 2023-08-04
doi: 10.1088/2752-5724/ace3dd

  • 1 School of Physical Sciences, Great Bay University, Dongguan 523000, People’s Republic of China

  • 2 Department of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, People’s Republic of China

  • 3 Hunan Institute of Metrology and Test, Changsha 410014, People’s Republic of China

Funds:

This research is supported by the open research fund of Songshan Lake Materials Laboratory 2022SLABFN06. Yue Niu acknowledges the support from the National Natural Science Foundation of China (51902109), Basic Research Program of Guangzhou 202201010546 and Special Funds for the Cultivation of Guangdong college students’ Scientific and Technological Innovation (‘Climbing Program’, pdjh2021b0136). Sha Liu acknowledges the support from National Nature Science Foundation of China (No. 52003091), the Guangdong Basic and Applied Basic Research Foundation (No. 2022A1515140155) for financial support.

    Abstract
  • Organic electronics have gained significant attention in the field of biosensors owing to their immense potential for economical, lightweight, and adaptable sensing devices. This review explores the potential of organic electronics-based biosensors as a revolutionary technology for biosensing applications. The focus is on two types of organic biosensors: organic field effect transistor (OFET) and organic electrochemical transistor (OECT) biosensors. OFET biosensors have found extensive application in glucose, DNA, enzyme, ion, and gas sensing applications, but suffer from limitations related to low sensitivity and selectivity. On the other hand, OECT biosensors have shown superior performance in sensitivity, selectivity, and signal-to-noise ratio, owing to their unique mechanism of operation, which involves the modulation of electrolyte concentration to regulate the conductivity of the active layer. Recent advancements in OECT biosensors have demonstrated their potential for biomedical and environmental sensing, including the detection of neurotransmitters, bacteria, and heavy metals. Overall, the future directions of OFET and OECT biosensors involve overcoming these challenges and developing advanced devices with improved sensitivity, selectivity, reproducibility, and stability. The potential applications span diverse fields including human health, food analysis, and environment monitoring. Continued research and development in organic biosensors hold great promise for significant advancements in sensing technology, opening up new possibilities for biomedical and environmental applications.
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